Last names starting with "O"
- Class of 1971 Patrice O'Toole
- Class of 2006 Patrick Obregon
- Class of 1988 Joe Obrien
- Annabelle Ocha
- Class of 1982 Maureen Oconnor
- Class of 1989 Crystal Ollek
- Class of 2006 Henry Ollie Jr
- Class of 1974 Elaine Olshefski
- Class of 2009 Okezie Onukwubiri
- Class of 1970 Sheila Oregan
- Class of 1986 Valerie Orr
- Class of 1991 Mike Orsini
- Class of 2016 Alice Oshinrongboye
- Class of 2000 Jennifer Osterhout (formerly Yancey)
- Michael Otis
- Class of 2012 Brianna Owens
- Class of 1977 David Owens
- Class of 1977 Terri Owens
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